Enlarged Prostate or Andropause? How to Tell What’s Really Going On After 50
Many men over 50 start noticing changes they did not expect.
Maybe you wake up several times at night to urinate. Maybe your energy feels lower than before. Or maybe your mood, sleep, or sexual health feels different.
It is easy to blame everything on aging. However, some symptoms may point to an enlarged prostate. Others may relate to low testosterone, sometimes called andropause.
The problem is that these conditions can overlap. That can make it hard to know what is really happening.
The good news is simple: you do not have to guess. With the right medical evaluation, you can understand the cause and choose the best treatment path.
What Is an Enlarged Prostate?
An enlarged prostate is called benign prostatic hyperplasia, or BPH.
BPH means the prostate has grown larger, but the growth is not cancer. It is very common as men age.
The prostate sits below the bladder and surrounds the urethra. Therefore, when it grows, it can press on the urinary channel.
As a result, many men start having trouble with urination. Johns Hopkins Medicine explains that BPH can obstruct urine flow through the urethra and cause bothersome urinary symptoms.
Common symptoms of an enlarged prostate
BPH usually causes urinary symptoms. These symptoms can start slowly and become more frustrating over time.
Common signs include:
- Frequent urination
- Urgent need to urinate
- Waking up at night to urinate
- Weak urine stream
- Trouble starting urination
- Dribbling after urination
- Feeling that the bladder is not fully empty
Mayo Clinic lists these symptoms as common signs of benign prostatic hyperplasia. It also notes that some men may develop urinary tract infections, blood in the urine, or inability to urinate.
When prostate symptoms affect daily life
Many men adapt to their symptoms without realizing it.
They avoid long drives. They look for bathrooms everywhere. They stop drinking water before leaving home.
Over time, these habits can affect sleep, confidence, work, travel, and intimacy.
That is why persistent urinary symptoms deserve medical attention. They are common, but they are not something men should simply ignore.
What Is Andropause?
Andropause is a common term for age-related testosterone decline.
Mayo Clinic explains that some men develop symptoms as testosterone decreases. These symptoms can include lower sexual desire, fewer erections, hot flashes, and sweats.
Andropause is not always the right medical diagnosis. Doctors often use terms like low testosterone or male hypogonadism.
Common symptoms of low testosterone after 50
Low testosterone can affect energy, mood, body composition, and sexual health.
Possible symptoms include:
- Low energy
- Reduced sexual desire
- Erectile dysfunction
- Depressed mood
- Trouble focusing
- Loss of muscle mass
- Increase in body fat
- Hot flashes or sweats
- Lower bone density
Male hypogonadism can also cause less muscle mass, reduced body hair, infertility, and bone loss. Severe cases may affect focus and cause hot flashes.
Why men often miss the signs
Many men think low energy, weight gain, or lower desire are just “normal aging.”
Sometimes they are. However, sometimes they point to a hormone issue, sleep problem, medication effect, or another medical condition.
That is why a blood test and medical evaluation matter. Symptoms alone cannot confirm low testosterone.
Enlarged Prostate vs. Andropause: What Is the Difference?
BPH and low testosterone can both appear after 50. However, they usually affect the body in different ways.
An enlarged prostate mainly affects urination. Andropause mainly affects energy, mood, body composition, and sexual health.
Still, the two can feel connected because both can disrupt sleep, confidence, and quality of life.
A simple way to compare symptoms
| Symptom | More likely BPH | More likely andropause |
| Frequent urination | Yes | No |
| Waking up at night to urinate | Yes | Sometimes indirectly |
| Weak urine stream | Yes | No |
| Trouble starting urination | Yes | No |
| Low energy | Sometimes, due to poor sleep | Yes |
| Lower sexual desire | Not usually the main sign | Yes |
| Erectile dysfunction | Sometimes related | Yes |
| Mood changes | Sometimes, due to poor sleep | Yes |
| Feeling bladder is not empty | Yes | No |
| Loss of muscle mass | No | Yes |
This comparison can help, but it does not replace a diagnosis.
A man can also have both conditions at the same time. Therefore, a complete evaluation is the smartest first step.
Why Symptoms After 50 Should Not Be Ignored
Men often wait too long before asking for help.
Some feel embarrassed. Others hope symptoms will improve on their own. Many just get used to waking up several times every night.
However, untreated BPH can become more serious in some men. Mayo Clinic notes that less common BPH symptoms can include urinary tract infection, blood in the urine, or inability to urinate.
Also, poor sleep can affect energy, mood, concentration, and overall health.
If your symptoms affect your daily routine, they deserve attention.
You should seek medical care sooner if you notice:
- Blood in the urine
- inability of emptying the bladder
- Painful urination
- Inability to urinate
- Fever with urinary symptoms
- Sudden worsening of urinary problems
- Severe sleep disruption from nighttime urination
These signs may need prompt medical attention.
How Doctors Find Out What Is Really Going On
A proper diagnosis usually starts with a conversation.
Your doctor may ask about your urinary habits, sleep, sexual health, medications, and medical history.
Then, depending on your symptoms, your evaluation may include:
- Urine testing
- Blood tests
- PSA testing
- Prostate exam
- Testosterone blood test
- Imaging
- Urinary flow studies
- Review of medications and lifestyle factors
The goal is to diagnose your condition and to understand how much it affects your life.
Mayo Clinic explains that BPH treatment depends on prostate size, age, overall health, and symptom severity.
Why many men look for minimally invasive options
Many men want relief, but they also want to avoid major surgery.
They may worry about downtime, hospital stays, bleeding, or sexual side effects.
That is where minimally invasive options can become important.
At SFVA, men with enlarged prostate symptoms may be evaluated for Prostate Artery Embolization, also known as PAE.
What Is Prostate Artery Embolization?
Prostate Artery Embolization is a minimally invasive procedure for selected men with BPH.
During PAE, an interventional radiologist guides a tiny catheter through the blood vessels. Then, the doctor reduces blood flow to the enlarged prostate tissue.
Over time, the prostate shrinks. As pressure improves, urinary symptoms improve.
The Society of Interventional Radiology (SIR), along with several international medical societies, recognizes Prostatic Artery Embolization (PAE) as an effective treatment option for appropriately selected men with benign prostatic hyperplasia (BPH).
PAE may be especially beneficial for men with very large prostates, recurrent bleeding caused by an enlarged prostate, or those who are not ideal candidates for surgery or general anesthesia. It is also an attractive option for patients who wish to avoid the risks associated with traditional surgical treatments and for those who want to preserve sexual function while achieving meaningful relief from urinary symptoms.
Benefits of PAE
For the right candidate, PAE offers several advantages.
These may include:
- No surgery
- No hospital stay
- Out of patient in office treatment
- No scalpel
- Shorter recovery
- Lower impact on daily routine
- A prostate-focused approach
- Potential preservation of sexual function
However, PAE is not right for every man. A specialist must review symptoms, anatomy, prostate size, and overall health.
Can Enlarged Prostate and Andropause Happen Together?
Yes. A man can have BPH and low testosterone at the same time.
For example, nighttime urination from BPH can ruin sleep. Poor sleep can then worsen fatigue, mood, and sexual health.
At the same time, low testosterone can reduce energy and confidence. That can make urinary symptoms feel even more frustrating.
That is why men over 50 should avoid self-diagnosing. A complete evaluation can separate the causes and guide better care.
When to Talk to a Vascular Specialist About PAE
You may want to ask about Prostate Artery Embolization if urinary symptoms affect your life.
This is especially true if you:
- Wake up often at night to urinate
- Feel frustrated by frequent bathroom trips
- Have a weak or interrupted stream
- Want to avoid surgery
- Have not found enough relief with medication
- Have concerns about recovery time
- Want to explore minimally invasive options
At South Florida Vascular Associates, Dr. William Julien brings more than 30 years of experience in advanced vascular and minimally invasive procedures.
His team helps patients understand their options clearly, step by step.
Sources for Website Reference
Mayo Clinic — Benign Prostatic Hyperplasia Symptoms and Causes
https://www.mayoclinic.org/diseases-conditions/benign-prostatic-hyperplasia/symptoms-causes/syc-20370087
Mayo Clinic — Benign Prostatic Hyperplasia Diagnosis and Treatment
https://www.mayoclinic.org/diseases-conditions/benign-prostatic-hyperplasia/diagnosis-treatment/drc-20370093
Mayo Clinic — Male Menopause: Myth or Reality?
https://www.mayoclinic.org/healthy-lifestyle/mens-health/in-depth/male-menopause/art-20048056
Mayo Clinic — Male Hypogonadism Symptoms and Causes
https://www.mayoclinic.org/diseases-conditions/male-hypogonadism/symptoms-causes/syc-20354881
Johns Hopkins Medicine — Benign Prostatic Hyperplasia
https://www.hopkinsmedicine.org/health/conditions-and-diseases/benign-prostatic-hyperplasia-bph
NIDDK — Enlarged Prostate / Benign Prostatic Hyperplasia
https://www.niddk.nih.gov/health-information/urologic-diseases/prostate-problems/enlarged-prostate-benign-prostatic-hyperplasia
Society of Interventional Radiology — Position Statement on Prostatic Artery Embolization
https://www.sirweb.org/for-press/sir-publishes-multisociety-position-statement-on-prostatic-artery-embolization/
Dr. Julien has performed more than 40,000 vascular procedures across a 30-year career. Double board-certified in Interventional Radiology and Diagnostic Radiology by the American Board of Radiology, he is the co-founder and past president of the Outpatient Endovascular & Interventional Society, a national faculty speaker at SIR, TCT, VIVA, and the Southeastern Angiographic Society, and a published author. Named a Boca Magazine Top Doctor 2025.